Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 5 Cortical hand bone loss and baseline serological biomarkers (univariate logistic regression analyses)

From: Antibodies to cyclic citrullinated protein and erythrocyte sedimentation rate predict hand bone loss in patients with rheumatoid arthritis of short duration: a longitudinal study

  One-year cortical hand bone loss Two-year cortical hand bone loss Five-year cortical hand bone loss
  OR
(95% CI)
P value OR
(95% CI)
P value OR
(95% CI)
P value
Age (years) 1.0
(1.0 to 1.0)
0.15 1.0
(1.0 to 1.1)
0.02 1.1
(1.0 to 1.1)
0.01
Sex (female) 1.3
(0.6 to 2.7)
0.52 2.0
(0.9 to 4.5)
0.09 1.0
(0.3 to 3.5)
0.96
Disease duration (years) 1.0
(0.7 to 1.3)
0.85 1.1
(0.8 to 1.5)
0.69 1.1
(0.7 to 1.7)
0.66
HAQ 1.9
(1.1 to 3.4)
0.03 2.5
(1.3 to 5.0)
0.01 1.5
(0.6 to 3.7)
0.41
ESR (> 20 mm/h) 5.2
(2.4 to 11.1)
< 0.001 5.5
(2.2 to 13.7)
< 0.001 4.6
(1.2 to 17.0)
0.02
CRP (> 10 mg/l) 1.9
(0.9 to 4.1)
0.11 4.1
(1.3 to 12.3)
0.01 6.0
(0.8 to 47.5)
0.09
Anti-CCP (> 25 U/ml) 2.7
(1.4 to 5.5)
0.004 3.2
(1.5 to 7.0)
0.003 5.1
(1.5 to 17.0)
0.01
IgA RF (> 25 U/ml) 2.6
(1.2 to 5.7)
0.01 3.3
(1.3 to 8.5)
0.01 2.2
(0.6 to 8.3)
0.23
IgM RF (> 25 U/ml) 1.7
(0.8 to 3.3)
0.14 3.4
(1.5 to 7.8)
0.005 3.8
(1.0 to 14.2)
0.05
DMARD use 2.1
(1.0 to 4.3)
0.05 2.9
(1.3 to 6.3)
0.009 2.5
(0.8 to 7.4)
0.10
Prednisolone use 2.3
(1.1 to 4.6)
0.02 3.5
(1.5 to 8.1)
0.004 4.8
(1.2 to 17.8)
0.02
  1. Results from univariate logistic regression analyses. Dependent variable: cortical hand bone loss exceeding the least significant change (least significant change = -0.79%).
  2. Anti-CCP = antibodies to cyclic citrullinated peptide; CI = confidence interval; CRP = C-reactive protein; DMARD = disease-modifying antirheumatic drugs; ESR = erythrocyte sedimentation rate; HAQ = health assessment questionnaire; Ig = immunoglobulin; OR = odds ratio; RF = rheumatoid arthritis.