| Saline treated | Propentofylline treated |
---|
Normal | 6.3 ± 0.4 | 8.2 ± 0.5* |
Monoarthritic | 3.7 ± 0.6# | 7.5 ± 0.7* |
- Values are means ± standard error the mean of stimulating current required (in mA) in the NS, MS, NP and MP groups. Two-way analysis of variance (ANOVA) identified the propentofylline treatment (P ANOVA < 0.0001, F = 25.79) and the monoarthritic condition (P = 0.0065, F = 8.64) as significant factors influencing the stimulating current required for threshold activation of the C-reflex. No propentofylline treatment × monoarthritic condition interaction was observed (P ANOVA = 0.1016, F = 2.87). Significant differences (P < 0.01) between propentofylline- and saline-treated groups are denoted by asterisks, while significant differences between monoarthritic and normal groups (P < 0.01) are indicated by the superscript # (according to the Bonferroni post hoc test). n = 8 animals for each group.
- NP = normal rats receiving intrathecal propentofylline; NS = normal rats receiving intrathecal saline; MP = monoarthritic rats receiving intrathecal propentofylline; MS = monoarthritic rats receiving intrathecal saline.