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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Developments in the scientific understanding of rheumatoid arthritis

Figure 1

Shown is a T cell-APC interaction to illustrate biologic pathways involving rheumatoid arthritis-associated genes (indicated in italics). APC, antigen-presenting cell; IKK, IκB kinase; MHC, major histocompatibility complex; NF-κB, nuclear factor-κB; TCR, T-cell receptor; Th, T-helper; TLR, Toll-like receptor; TNFR2, type 2 TNF receptor.

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