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Table 2 Immunoprecipitation of the Smith antigen/ribonucleoprotein complex

From: Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus

Genotype

Treatment

Number

Sm/RNP (percentage)

WT

PBS

5

0 (0)

WT

Pristane

10

7 (70)

IFNAR2-/-

PBS

4

0 (0)

IFNAR2-/-

Pristane

10

0 (0)a

  1. aP < 0.005 versus wild-type (WT) pristane, Fisher exact test. IFNAR2, interferon-I receptor 2; PBS, phosphate-buffered saline; Sm/RNP, Smith antigen/ribonucleoprotein.
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Arthritis Research & Therapy

ISSN: 1478-6362

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