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Table 1 Demographic and central biomarker values at baseline for the evaluation population

From: Identification of progressors in osteoarthritis by combining biochemical and MRI-based markers

 

Females (48%)

Males (52%)

 

Healthy (n = 66)

KL > 0 (n = 72)

Healthy (n = 79)

KL > 0 (n = 70)

Age (years)

47 (17)

63 (12)***

49 (16)

65 (7)***

Height (cm)

166 (6)

164 (6)*

178 (7)

176 (7)

Weight (kg)

67 (12)

72 (12)*

81 (12)

88 (12)***

Body mass index (kg/m2)

24.3 (4.5)

26.9 (4.2)***

25.5 (3.4)

28.4 (4.0)***

Joint space width (mm)

3.8 (0.7)

3.3 (1.2)**

4.4 (0.7)

3.3 (1.6)***

Volume (MTF.VC) (mm3)

5,742 (1,265)

5,906 (1,081)

8,112 (1,216)

7,468 (1,693)**

CTX-II/Cr (μg/mmol)

0.20 (0.11 to 0.36)

0.23 (0.11 to 0.48)

0.19 (0.11 to 0.32)

0.23* (0.13 to 0.41)

  1. Demographic and central biomarker values at baseline for the 287 knees in the evaluation population (excluding the 25 knees used for training) divided by gender and by radiographic osteoarthritis status. Values presented as mean (standard deviation), or as geometric mean (± 1 standard deviation range) for the urinary collagen type II C-telopeptide marker normalized by creatinine levels (CTX-II/Cr). KL, Kellgren and Lawrence index; MTF.VC, medial tibio-femoral cartilage volume. The level of significance denotes for each gender the difference between the healthy group and the osteoarthritis group: *P < 0.05, **P < 0.01, ***P < 0.001.
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Arthritis Research & Therapy

ISSN: 1478-6362

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