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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc

Figure 4

Gene expression data. Histograms illustrating gene expression of (a) interleukin-1 (IL-1) and (b) tumour necrosis factor-alpha (TNF-α) in postmortem (PM) normal, PM degenerate and surgical degenerate human intervertebral disc. Relative gene expression was normalised to the housekeeping gene glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and plotted on a log scale. *P < 0.05; **P < 0.01. Scatterplots illustrating correlations in (c) IL-1 versus matrix metalloproteinase-10 (MMP-10) expression and (d) TNF-α versus MMP-10 expression in surgical degenerate samples.

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