Table 1 Arthritis scores of type II collagen/complete Freund's adjuvant-immunized T-cell receptor transgenic mice and total splenocyte counts at day 28
From: Reduced Fas ligand-expressing splenic CD5+B lymphocytes in severe collagen-induced arthritis
Mousea | Cage | Day 16b | Day 20 | Day 23 | Day 27 | Final score | Category | Total number of splenocytes |
|---|---|---|---|---|---|---|---|---|
1 | 1 | 0,0,0,0 | 0,0,1,2 | 3,0,3,3 | 3,0,3,3 | 9 | Severe | 8.00 × 107 |
3 | 1 | 0,0,0,0 | 0,0,0,1 | 0,1,0,0 | 3,3,0,0 | 6 | Moderate | 1.66 × 108 |
4 | 1 | 3,0,1,0 | 3,3,1,1 | 3,3,3,3 | 3,3,3,3 | 12 | Severe | 8.72 × 107 |
5 | 2 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0 | No arthritis | 1.47 × 108 |
6 | 2 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0 | No arthritis | 1.46 × 108 |
7 | 3 | 0,0,0,0 | 0,3,1,1 | 0,3,3,3 | 0,3,3,3 | 9 | Severe | 1.05 × 108 |
8 | 3 | 0,2,0,0 | 1,3,0,0 | 1,3,0,0 | 1,3,0,1 | 5 | Moderate | 1.66 × 108 |
9 | 3 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0,0,1,1 | 2 | Mild | 1.22 × 108 |
10 | 4 | 0,0,0,0 | 0,0,0,0 | 1,2,0,0 | 0,2,1,2 | 5 | Moderate | 1.56 × 108 |
11 | 4 | 0,0,0,0 | 0,0,0,0 | 3,0,1,2 | 3,0,1,3 | 7 | Severe | 5.52 × 107 |
12 | 5 | 0,0,0,0 | 0,0,1,0 | 0,0,1,0 | 0,0,1,0 | 1 | Mild | 1.25 × 108 |
13 | 5 | 0,0,0,0 | 0,0,0,0 | 1,1,0,1 | 2,1,0,2 | 5 | Moderate | 1.18 × 108 |
14 | 5 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0 | No arthritis | 7.12 × 107 |
15 | 6 | 0,0,0,0 | 0,0,0,0 | 0,0,0,1 | 0,3,1,3 | 7 | Severe | 6.72 × 107 |
16 | 6 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0,0,0,0 | 0 | No arthritis | 8.32 × 107 |
17 | 6 | 0,0,0,0 | 0,0,0,0 | 0,0,1,0 | 0,0,3,1 | 4 | Moderate | 8.00 × 107 |
18 | 7 | 0,0,0,0 | 0,0,0,0 | 1,2,0,1 | 1,3,1,3 | 8 | Severe | 9.68 × 107 |
19 | 7 | 0,0,0,0 | 0,0,0,0 | 0,3,0,0 | 0,3,3,3 | 9 | Severe | 6.40 × 107 |
20 | 7 | 0,0,0,0 | 0,0,1,1 | 0,0,2,3 | 0,0,2,3 | 5 | Moderate | 8.72 × 107 |