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Table 1 Arthritis scores of type II collagen/complete Freund's adjuvant-immunized T-cell receptor transgenic mice and total splenocyte counts at day 28

From: Reduced Fas ligand-expressing splenic CD5+B lymphocytes in severe collagen-induced arthritis

Mousea Cage Day 16b Day 20 Day 23 Day 27 Final score Category Total number of splenocytes
1 1 0,0,0,0 0,0,1,2 3,0,3,3 3,0,3,3 9 Severe 8.00 × 107
3 1 0,0,0,0 0,0,0,1 0,1,0,0 3,3,0,0 6 Moderate 1.66 × 108
4 1 3,0,1,0 3,3,1,1 3,3,3,3 3,3,3,3 12 Severe 8.72 × 107
5 2 0,0,0,0 0,0,0,0 0,0,0,0 0,0,0,0 0 No arthritis 1.47 × 108
6 2 0,0,0,0 0,0,0,0 0,0,0,0 0,0,0,0 0 No arthritis 1.46 × 108
7 3 0,0,0,0 0,3,1,1 0,3,3,3 0,3,3,3 9 Severe 1.05 × 108
8 3 0,2,0,0 1,3,0,0 1,3,0,0 1,3,0,1 5 Moderate 1.66 × 108
9 3 0,0,0,0 0,0,0,0 0,0,0,0 0,0,1,1 2 Mild 1.22 × 108
10 4 0,0,0,0 0,0,0,0 1,2,0,0 0,2,1,2 5 Moderate 1.56 × 108
11 4 0,0,0,0 0,0,0,0 3,0,1,2 3,0,1,3 7 Severe 5.52 × 107
12 5 0,0,0,0 0,0,1,0 0,0,1,0 0,0,1,0 1 Mild 1.25 × 108
13 5 0,0,0,0 0,0,0,0 1,1,0,1 2,1,0,2 5 Moderate 1.18 × 108
14 5 0,0,0,0 0,0,0,0 0,0,0,0 0,0,0,0 0 No arthritis 7.12 × 107
15 6 0,0,0,0 0,0,0,0 0,0,0,1 0,3,1,3 7 Severe 6.72 × 107
16 6 0,0,0,0 0,0,0,0 0,0,0,0 0,0,0,0 0 No arthritis 8.32 × 107
17 6 0,0,0,0 0,0,0,0 0,0,1,0 0,0,3,1 4 Moderate 8.00 × 107
18 7 0,0,0,0 0,0,0,0 1,2,0,1 1,3,1,3 8 Severe 9.68 × 107
19 7 0,0,0,0 0,0,0,0 0,3,0,0 0,3,3,3 9 Severe 6.40 × 107
20 7 0,0,0,0 0,0,1,1 0,0,2,3 0,0,2,3 5 Moderate 8.72 × 107
  1. aMouse #2 was sacrificed at day 20 due to malnourishment, which was believed to be related to a dental abnormality. This mouse had no signs of arthritis on day 20. bArthritis disease scoring is based on a 3-point scale for each paw: 0 = no inflammation, 1 = inflammation confined to digits, 2 = mild swelling of paw, and 3 = severe swelling encompassing paw, ankle, wrist, and/or knee joints. Scores shown for individual dates are in the following order: right fore paw, left fore paw, right hind paw, and left hind paw.