Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast-like synoviocytes from nitric oxide-induced apoptosis

Table 1 Clinical data of five patients with rheumatoid arthritis at the time of joint surgery ^a

Patient	Disease duration^b, months	Site of surgery	Medication
1	74	Knee	MTX 15 mg/wk, SSZ 1 g/d, Pd 5 mg/d
2	60	Knee	NSAIDs
3	97.5	Knee	Pd 10 mg/d
4	121	Knee	Pd 10 mg/d
5	180	Hip	HCQ 200 mg/d

^aAge of the patients was 57.0 ± 15.6 years (age range 35 to 73 years), and they were all female. ^bDisease duration is the time interval between symptom onset of rheumatoid arthritis and joint replacement surgery. HCQ, hydroxychlorquine; MTX, methotrexate; NSAID, nonsteroidal anti-inflammatory drug; Pd, prednisolone; SSZ, sulfasalazine.

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