Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study

Table 3 Serum TWEAK results for the Albert Einstein College of Medicine cohort (pg/ml)

	Serum TWEAK	Pvalue	AUC of ROC curve
SLE patients vs. healthy controls	15.87 (13.04 to 24.36), n = 66 vs. 23.56 (17.26 to 27.12), n = 19	0.034*	0.660
SLE + LN patients vs. SLE non-LN patients	16.42 (13.09 to 24.71), n = 23 vs. 15.72 (12.81 to 24.30), n = 43	0.747	-

Continuous variables presented as the median (interquartile range). LN, lupus nephritis; SLE, systemic lupus erythematosus The area under the curve (AUC) was calculated from nonparametric receiver operating characteristic (ROC) curves constructed to test the ability of serum TNF-like weak inducer of apoptosis (TWEAK) to distinguish between patients and healthy controls. *P < 0.05. The Mann- Whitney U test was used to compare between two groups.

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