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Table 2 Prediction of persistent synovitis, DMARD prescription and RA at one year in univariate logistic regression analyses

From: Positive anti-citrullinated protein antibody status and small joint arthritis are consistent predictors of chronic disease in patients with very early arthritis: results from the NOR-VEAC cohort

 

Dependent variable

 

Persistent synovitis

n = 98

DMARD prescription

n = 106

RA

n = 68

Baseline variables

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Age (years)

1.02 (1.01-1.04)

0.008*

1.02 (1.00-1.04)

0.017*

1.05 (1.03-1.07)

< 0.001*

Female gender

1.46 (0.91-2.33)

0.12*

1.06 (0.67-1.67)

0.80

1.12 (0.67-1.91)

0.67

68-SJC

1.08 (1.03-1.12)

< 0.001*

1.14 (1.09-1.20)

< 0.001*

1.15 (1.09-1.21)

< 0.001*

28-TJC

1.11 (1.06-1.16)

< 0.001*

1.19 (1.13-1.26)

< 0.001*

1.20 (1.13-1.27)

< 0.001*

ESR (mm/h)

1.00 (1.00-1.01)

0.41

1.01 (1.00-1.02)

0.09*

1.00 (0.99-1.01)

0.98

CRP (mg/l)

1.00 (0.99-1.00)

0.18*

1.00 (1.00-1.01)

0.80

1.00 (0.99-1.00)

0.23*

ACPA positivity

7.13 (3.73-13.64)

< 0.001*

16.9 (7.94-35.8)

< 0.001*

57.6 (24.6-134.5)

< 0.001*

IgM RF positivity

5.65 (2.78-11.5)

< 0.001*

11.8 (5.34-26.4)

< 0.001*

28.5 (12.3-65.8)

< 0.001*

Morn. stiffness >1 hour

1.74 (1.08-2.79)

0.023*

2.71 (1.68-4.38)

< 0.001*

2.47 (1.40-4.37)

0.002*

HAQ (0-3)

1.61 (1.15-2.27)

0.006*

2.22 (1.57-3.14)

< 0.001*

1.63 (1.11-2.39)

0.012*

Small joint arthritis§

3.72 (2.29-6.05)

< 0.001*

8.19 (4.83-13.9)

< 0.001*

20.5 (8.58-48.9)

< 0.001*

Ever smoker

1.19 (0.74-1.92)

0.48

1.33 (0.83-2.13)

0.24*

2.71 (1.44-5.09)

0.002*

  1. § Metacarpo-phalangeal joint, proximal interphalangeal joint, or metatarso-phalangeal joint joint swelling.*P < 0.25, variable selected for inclusion in multivariate analyses.
  2. ACPA = anti-citrullinated protein antibody; CI = confidence interval; CRP = C-reactive protein; DMARD = disease-modifying anti-rheumatic drugs; ESR = erythrocyte sedimentation rate; HAQ = Health Assessment Questionnaire; OR = odds ratio; RA = rheumatoid arthritis; RF = rheumatoid factor; SJC = swollen joint count; TJC = tender joint count.
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Arthritis Research & Therapy

ISSN: 1478-6362

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