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Table 3 Prediction of persistent synovitis, DMARD prescription and RA in final multivariate logistic regression models

From: Positive anti-citrullinated protein antibody status and small joint arthritis are consistent predictors of chronic disease in patients with very early arthritis: results from the NOR-VEAC cohort

 

Dependent variable

 

Persistent synovitis

n = 98

DMARD start

n = 106

RA

n = 68

Baseline variables

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Age (years)

1.01 (0.99-1.03)

0.18

1.00 (0.98-1.02)

0.70

1.04 (1.01-1.08)

0.018

Female gender

1.20 (0.68-2.12)

0.52

0.99 (0.54-1.79)

0.97

1.24 (0.51-3.01)

0.64

ACPA positivity

4.50 (2.17-9.33)

< 0.001

8.11 (3.55-18.6)

< 0.001

19.3 (6.84-54.4)

< 0.001

IgM RF positivity

-

-

-

-

5.02 (1.47-17.1)

0.010

Small joint arthritis§

2.11 (1.17-3.81)

0.013

3.86 (2.02-7.37)

< 0.001

3.45 (1.21-9.90)

0.021

HAQ

1.73 (1.12-2.68)

0.014

1.75 (1.13-2.74)

0.012

-

-

28-TJC

-

-

1.06 (1.00-1.13)

0.064

1.09 (1.02-1.16)

0.012

CRP (mg/l)

0.99 (0.98-1.00)

0.042

-

-

-

-

Constant

0.069

-

0.075

-

0.003

-

  1. § Metacarpo-phalangeal joint, proximal interphalangeal joint, or metatarso-phalangeal joint joint swelling.
  2. ACPA = anti-citrullinated protein antibody; CI = confidence interval; CRP = C-reactive protein; DMARD = disease-modifying anti-rheumatic drugs; HAQ = Health Assessment Questionnaire; OR = odds ratio; RA = rheumatoid arthritis; RF = rheumatoid factor; TJC = tender joint count.