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Table 2 Chemokine-receptor expression in synovial fluid and peripheral blood CD27 + switch memory B cells

From: Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis

Chemokine receptors

Synovial fluida(n = 13)

Peripheral blooda(n = 13)

Pvalueb

CCR1

7.0 (2.0-18)

6.5 (3.3-8.5)

ns

CCR2

6.7 (2.4-28)

5.8 (4.4-6.9)

ns

CCR3

6.9 (2.0-27.3)

6.5 (5.2-7.7)

ns

CCR4

6.6 (2.3-21.5)

5.3 (2.9-6.4)

ns

CCR5

25.0 (5.5-45)

36.8 (27.8-69.7)

0.0003

CCR6

18.7 (8.0-45)

3.4 (1.6-5.3)

0.019

CCR7

22.6 (8.0-50)

65.1 (40.2-72.7)

0.001

CCR8

24.0 (8.3-50)

7.1 (5.8-10.6)

0.0002

CCR9

23.1 (6.1-76)

6.2 (4.9-8)

0.004

CXCR1

9.7 (4.0-27.0)

3.0 (1.2-4.1)

0.001

CXCR2

44.4 (21.8-55.7)

6.8 (3.4-10.0)

0.002

CXCR3

83.6 (68.0-92.3)

7.3 (6.2-13.5)

0.002

CXCR4

49.0 (37.3-63.6)

72.2 (35.8-85.3)

ns

CXCR5

39.3 (20.7-66.0)

79.5 (70.0-83.5)

0.001

  1. aResults represent median percentage of positive cells, as assessed with flow cytometry. Values in parentheses are minimum and maximum values. bP values were calculated by comparing the results of JIA SF and PB cell staining. ns = not significant.