Figure 5From: Effect of small interference RNA (siRNA) for ADAMTS5on intervertebral disc degeneration in the rabbit anular needle-puncture modelMagnetic resonance imaging (MRI) findings after small interfering RNA (siRNA) oligonucleotide injection in the rabbit anular puncture model of disc degeneration. MRI examinations were performed on all spinal columns isolated from the rabbits ex vivo at death 8 weeks after the siRNA oligonucleotide injection. In these representative MRIs, the T2 signal intensity in the nucleus pulposus of the ADAMTS5 siRNA-injected discs was stronger than that in the control siRNA-injected discs.Back to article page