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Figure 7 | Arthritis Research & Therapy

Figure 7

From: Altered peptide ligands inhibit arthritis induced by glucose-6-phosphate isomerase peptide

Figure 7

Co-immunization with altered peptide ligands suppresses production of antibodies to mouse glucose-6-phosphate isomerase. Sera were taken on day 28 from mice co-immunized with 10 μg glucose-6-phosphate isomerase hGPI325--339 and 50 μg each altered peptide ligand (APL), and the titers of anti-mouse GPI IgG and IgG isotype were analyzed by ELISA. Each symbol represents a single mouse. Data presented as mean optimal density ± standard deviation. *P < 0.01, **P < 0.005, ***P < 0.001 (Mann--Whitney U test).

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