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Table 2 Haplotype distribution in patients with AS and controls

From: HLA-E gene polymorphism associates with ankylosing spondylitis in Sardinia

Haplotypes rs1264457/rs2074505/rs2074503/rs2269709 Random controls HLA-B27 controls P HLA-B27 patients with AS p1 p2
   Non B*2709 (B*2709) n = 135 n = 40     
AAGA 0.42 0.52 (0.59)* 9 × 10-4 0.68 2 × 10-11 3 × 10-4
GGAG 0.24 0.23 (0.16) ns 0.12 1 × 10-4 0.001
GGGA 0.14 0.10 (0.10) ns 0.05 7 × 10-4 ns
Others 0.20 0.15 (0.15) ns 0.15 ns ns
  1. in brackets = haplotype frequencies referring to 40 HLA-B*2709 positive subjects which had been enclosed in the statistical analysis; p1 = HLA-B27 positive patients with AS vs random controls; p2 = HLA-B27 positive patients with AS vs the pool of the HLA-B27 positive controls. AS = ankylosing spondylitis.