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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Intradiscal injection of simvastatin retards progression of intervertebral disc degeneration induced by stab injury

Figure 4

Weight, sGAG, and DNA content in the NP of different experimental groups at two weeks after drug injection. Discs in the treatment groups were injected with either 2 μL of gel alone or gel loaded with simvastatin (SIM; 5 mg/mL) at four weeks after disc stab with 21-G needle. * P < 0.05 and ** P < 0.01 when compared with intact control group;# P < 0.05 when compared with stabbed group; + P < 0.05 when compared with gel-alone-treated group. NP = nucleus pulpous; sGAG = glycosaminoglycan.

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