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Table 1 Comparison of group 1 and group 2 patients

From: Safety of TNF-blocking agents in rheumatic patients with serology suggesting past hepatitis B state: results from a cohort of 21 patients

Patient characteristics Group 1 (n = 6) Group 2 (n = 15)
Mean age, years 56 57
Percentage of female patients 77 77
Percentage of patients with rheumatoid arthritis 77 53
Mean anti-HBsAb titre, IU/L 302 753
Mean duration of disease, years 13 10
Mean duration of treatment, months 34 24
Association with methotrexate (mean dosage: 10 mg/week) 4 6
Association with corticosteroid 1 4
Two successive anti-TNFα inhibitors 2 4
Three successive anti-TNFα inhibitors 0 2
  1. Group 1 patients underwent a strong decrease in anti-HBsAb and group 2 patients did not. TNFα, tumor necrosis factor-alpha.