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Table 1 Comparison of group 1 and group 2 patients

From: Safety of TNF-blocking agents in rheumatic patients with serology suggesting past hepatitis B state: results from a cohort of 21 patients

Patient characteristics

Group 1 (n = 6)

Group 2 (n = 15)

Mean age, years

56

57

Percentage of female patients

77

77

Percentage of patients with rheumatoid arthritis

77

53

Mean anti-HBsAb titre, IU/L

302

753

Mean duration of disease, years

13

10

Mean duration of treatment, months

34

24

Association with methotrexate (mean dosage: 10 mg/week)

4

6

Association with corticosteroid

1

4

Two successive anti-TNFα inhibitors

2

4

Three successive anti-TNFα inhibitors

0

2

  1. Group 1 patients underwent a strong decrease in anti-HBsAb and group 2 patients did not. TNFα, tumor necrosis factor-alpha.