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Table 1 Comparison of baseline clinical characteristics between the chicken type II collagen group and the methotrexate group

From: A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis

Variables CCII (n = 296) MTX (n = 158) Pvalue
Gender, male/female 55/241 30/128 0.983
Age, years 47.11 ± 10.55 47.06 ± 11.14 0.967
Duration of rheumatoid arthritis, years 1.63 ± 0.75 1.72 ± 0.52 0.949
Body temperature, °C 36.66 ± 0.38 36.65 ± 0.39 0.892
Pain (VASa) 6.02 ± 1.43 5.91 ± 1.76 0.528
Morning stiffness, minutes 99.26 ± 25.14 104.89 ± 26.42 0.277
Tender joint count 13.34 ± 6.43 14.09 ± 6.82 0.233
Swollen joint count 10.38 ± 6.63 10.57 ± 7.25 0.773
HAQb 0.82 ± 0.56 0.86 ± 0.55 0.454
Physician's assessment (VAS) 5.83 ± 1.54 5.78 ± 1.26 0.892
Patient's assessment (VAS) 6.01 ± 1.51 6.06 ± 1.71 0.731
ESRc, mm/hour 38.18 ± 27.58 42.51 ± 29.37 0.118
C-reactive protein, mg/L 17.52 ± 8.27 23.24 ± 9.81 0.306
Rheumatoid factor, U/mL 203.65 ± 61.95 198.99 ± 21.31 0.115
  1. The same variables were compared between the chicken type II collagen (CCII) group and the methotrexate (MTX) group. Fisher exact test was used for categorical variables, and t analysis of variance was used for continuous variables. cESR, erythrocyte sedimentation rate; bHAQ, health assessment questionnaire; MTX, methotrexate; aVAS, visual analogue scale.