A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis

Table 4 Comparison of adverse events between the chicken type II collagen group and the methotrexate group at 12 and 24 weeks

Weeks	Groups	Adverse events	Rate of adverse events	Chi-square	Pvalue^a
12	CCII (n = 326)	18	5.52%	1.974	0.048
	MTX (n = 177)	15	8.47%
24	CCII (n = 326)	18	5.52%	2.001	0.036
	MTX (n = 177)	17	9.60%

ISSN: 1478-6362