Adverse events | CCII (n = 326) | MTX (n = 177) |
---|---|---|
   Nausea, vomiting | 6 | 13 |
   Abdominal pain, epigastric discomfort | 17 | 11 |
   Diarrhea | 0 | 2 |
   Liver dysfunction | 6 | 10 |
   Headache, dizziness | 3 | 5 |
   Itching, rash | 5 | 1 |
   Blood in urine | 2 | 3 |
   Constipation | 1 | 0 |
   Edema | 2 | 1 |
   Alopecia | 0 | 1 |
   Decrease in white blood cell count | 1 | 5 |
   Decrease in platelet count | 0 | 1 |
Sum of events | 43 | 53 |