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Table 5 Incidence of adverse events

From: A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis

Adverse events CCII (n = 326) MTX (n = 177)
   Nausea, vomiting 6 13
   Abdominal pain, epigastric discomfort 17 11
   Diarrhea 0 2
   Liver dysfunction 6 10
   Headache, dizziness 3 5
   Itching, rash 5 1
   Blood in urine 2 3
   Constipation 1 0
   Edema 2 1
   Alopecia 0 1
   Decrease in white blood cell count 1 5
   Decrease in platelet count 0 1
Sum of events 43 53
  1. CCII, chicken type II collagen; MTX, methotrexate.