Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study

Table 4 Association between lipids and annual change in total tibial cartilage volume

	Univariate analysis, regression coefficient (95% CI)	Pvalue	Multivariate analysis, regression coefficient (95% CI)^a	Pvalue
Total cholesterol	-0.24 (-12.77, 12.28)	0.97	-1.77 (-11.35, 14.88)	0.79
Ln triglycerides	0.70 (-32.48, 33.88)	0.97	12.6 (-24.12, 49.32)	0.49
Ln HDL	-4.78 (-56.43, 46.88)	0.85	-15.96 (-72.28, 40.37)	0.58
Ln LDL	3.16 (-48.06, 54.39)	0.90	13.12 (-41.2, 67.45)	0.63
Total/HDL ratio	-0.67 (-11.57, 10.24)	0.90	2.58 (-9.5, 14.68)	0.67

^aAnnual change in total tibial cartilage volume (in microlitres) for each unit increase in total cholesterol, natural logarithm (Ln) of triglycerides, natural logarithm of high-density lipoprotein (HDL) or low-density lipoprotein (LDL) or for the total/HDL ratio after adjusting for age and body mass index. CI, confidence interval.

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