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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs

Figure 4

Localization of matrix metalloproteinase 28 in the extracellular matrix of the inner annulus. Localization of matrix metalloproteinase 28 in the extracellular matrix in the inner annulus of a Thompson Grade V disc. Both (a) relatively small, localized pericellular (arrows) concentrations and (b) diffuse larger localization regions were present in the disc matrix of more degenerated discs. *Nearby presence of focal regions of matrix loss in a Thompson Grade III disc. Magnification: (a) ×325, (b) ×110.

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