Figure 4From: Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discsLocalization of matrix metalloproteinase 28 in the extracellular matrix of the inner annulus. Localization of matrix metalloproteinase 28 in the extracellular matrix in the inner annulus of a Thompson Grade V disc. Both (a) relatively small, localized pericellular (arrows) concentrations and (b) diffuse larger localization regions were present in the disc matrix of more degenerated discs. *Nearby presence of focal regions of matrix loss in a Thompson Grade III disc. Magnification: (a) ×325, (b) ×110.Back to article page