Skip to main content
Figure 5 | Arthritis Research & Therapy

Figure 5

From: A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis

Figure 5

Bone density measured with a densitometer suitable for use with small animals. Zoledronic acid (ZA) significantly increased the bone density of the femur and spine in rats. We found no difference between the control and methotrexate (MTX) groups. Treatment with a combination of MTX + ZA was as effective as treatment with ZA alone. Values are the mean ± standard deviation. *P < 0.05 versus computed tomography (CT) group; +P < 0.05 versus MTX group.

Back to article page