Skip to main content
Figure 6 | Arthritis Research & Therapy

Figure 6

From: A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis

Figure 6

Micro-CT analysis. (a) Representative micro-computed tomography (CT) image of the distal tibia for each rat group. (b) Histomorphometric analysis of the distal tibia for the various treatment groups, showing a significant increase in bone volume (BV)/tissue volume (TV) ratio, cortical thickness, trabecular and cortical bone volume and trabecular thickness in rats treated with zoledronic acid (ZA). Methotrexate (MTX) had no effect on histomorphometric parameters. Values are the mean ± standard deviation. **P < 0.005 versus CT group; ++P < 0.005 versus MTX group.

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us