Skip to main content
Figure 6 | Arthritis Research & Therapy

Figure 6

From: RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFα or anti-IL-1 therapies

Figure 6

Serum markers and mediators of inflammation in collagen-induced arthritis (CIA) rats. Values were determined on day 14 post onset, 10 days after the initiation of treatment. Data represent means ± standard error of the means, n = 8/group. cSignificantly different from control (non-arthritic) rats, P < 0.05. vSignificantly different from vehicle (Veh)-treated arthritic rats, P < 0.05. oSignificantly different from osteoprotegerin (OPG)-treated arthritic rats, P < 0.05. α1AGP, acute-phase protein alpha-1-acid glycoprotein; CCL2, chemokine (C-C motif) ligand 2; CIA, collagen-induced arthritis; CRP, C-reactive protein; PGE2, prostaglandin E2.

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us