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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Local expression of tumor necrosis factor-receptor 1:immunoglobulin G can induce salivary gland dysfunction in a murine model of Sjögren's syndrome

Figure 1

In vitro biological activity assay for TNFR1:IgG. The biological activity of the TNFR1:IgG was determined by adding supernate from TNFR1:IgG expressing cells to WEHI fibrosarcoma cells and measuring its ability to block TNF induced apoptosis in these cells. Increasing concentrations of TNFR1:IgG resulted in inhibiting TNF (62.5 pg/ml) induced apoptosis of WEHI cells. Data shown are mean ± SD (N = 2 independent experiments).

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