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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Separating therapeutic efficacy from glucocorticoid side-effects in rodent arthritis using novel, liposomal delivery of dexamethasone phosphate: long-term suppression of arthritis facilitates interval treatment

Figure 4

Effects of liposomal and free dexamethasone phosphate on blood glucose, liver enzymes and haematology. (a) Glucose levels as a percentage of the initial blood value in arthritic animals following treatment with liposomal dexamethasone phosphate (DXM-P), free DXM-P, or saline. (b) Values of liver enzymes alkaline phosphatase (AP), alanine aminotransferase (ALAT) and aspartate aminotransferase (ASAT) after treatment with liposomal DXM-P, free DXM-P, or saline. (c) Percentage of polymorphonuclear neutrophilic leukocytes (PMNs) and lymphocytes in the blood of arthritic animals following treatment with liposomal DXM-P, free DXM-P, or saline. *P ≤ 0.05 Mann-Whitney U test versus saline-treated inflamed animals. n = 6 for all groups; mean ± standard error of the mean.

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