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Table 1 Studies documenting the detrimental effects of IFN-γ in murine systemic lupus erythematosus

From: The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity

Strain Experimental manipulations References
(CBA × C57/BL10)F1 trIFN-γ [29,30]
B × W IFN-γ [38,39]
B × W Anti-IFN-γ mAb [38]
B × W sIFN-γR [39]
B × W IFN-γR-/- [43]
MRL-Faslpr sIFN-γR/Fc [47]
MRL-Faslpr IFN-γ-/- [41,42]
MRL-Faslpr IFN-γR-/- [44]