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Table 1 Sensitivity and specificity of the CCP2 test

From: The use of citrullinated peptides and proteins for the diagnosis of rheumatoid arthritis

Patient group

n

Anti-CCP2(+)

Sensitivity (%)

Specificity (%)

RA total

17,359

12,431

71.6

 

   Early

4,379

2,677

61.1

 

   Established

12,980

9,754

75.1

 

Controls

20,222

960

4.7

95.3

   Non-RA

15,461

911

5.9

94.1

   Healthy

4,761

49

1.0

99.0

  1. The cumulative sensitivity and specificity of the CCP2 test is based on the results of 154 independent studies published between 2002 and June 2009. Separation into early and established rheumatoid arthritis (RA) was adapted from the original studies.