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Table 1 Sensitivity and specificity of the CCP2 test

From: The use of citrullinated peptides and proteins for the diagnosis of rheumatoid arthritis

Patient group n Anti-CCP2(+) Sensitivity (%) Specificity (%)
RA total 17,359 12,431 71.6  
   Early 4,379 2,677 61.1  
   Established 12,980 9,754 75.1  
Controls 20,222 960 4.7 95.3
   Non-RA 15,461 911 5.9 94.1
   Healthy 4,761 49 1.0 99.0
  1. The cumulative sensitivity and specificity of the CCP2 test is based on the results of 154 independent studies published between 2002 and June 2009. Separation into early and established rheumatoid arthritis (RA) was adapted from the original studies.