From: The use of citrullinated peptides and proteins for the diagnosis of rheumatoid arthritis
 |  |  | Sensitivity at stratified specificity (%) | ||||
---|---|---|---|---|---|---|---|
Reference | Number of patients (RA/control) | Stratified specificity (%) | CCP2 | CCP3 | MCVa | Other | RF |
Bizzaro and colleagues [23] | 100/202 | 98.5 | 64 to 74b, c, d, e, f | 67g, h | 62 | 41 to 47i, j, k | 17 |
Coenen and colleagues [44]; Bossuyt, personal communication | 102/196 | 95.0 | 76.2 to 77.0b, d, e | 75.5g | 65.7 | 69.3j | ND |
Damjanovska and colleagues [50]; Thabet, personal communication | 566/351 | 93.4 | 56.9e | 56.2h | 52.5 | ND | ND |
Dejaco and colleagues [51] | 164/303 | 98.7 | 70.1d | ND | 53.7 | ND | ND |
Innala and colleagues [41] | 210/102 | 98.0 | 80.4c | 78.5 to 79.0g, h | 69.0 | ND | ND |
Mutlu and colleagues [37] | 93/83 | 98.8 | 57.0 to 60.2l, f | 60.2g | 29 | ND | 48.4 |
Soos and colleagues [52] | 119/118 | 95 | 74.8 | ND | 69.7 | ND | 33.6 |
Vander Cruyssen and colleagues [53] | 272/463 | 98.5 | 67.4 to 68.0e | ND | ND | ND | 16.3 to 24.4 |
Vander Cruyssen and colleagues [42] (early arthritis) | 92/463 | 98.7 | 61.6 to 67.4d, e | 58.1g | ND | ND | ND |
Vander Cruyssen and colleagues [42] (established RA) | 180/463 | 98.7 | 65.2 to 77.4d, e | 67.1g | ND | ND | ND |
Average | Â | 97.3 | 69.2 | 66.1 | 57.4 | Â | 29.9 |