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Table 4 Previously identified marker
| Gene description | Gene symbol | AC mean | AF mean | NP mean | Fold change (NP/AC) | Fold change (NP/AF) | Fold change (NP/AC&AF) |
|---|---|---|---|---|---|---|---|
| matrix metallopeptidase 2 | MMP2 | 200.20 | 155.41 | 121.53 | -1.65 | -1.28 | -1.56 |
| solute carrier family 2, member 1 | SLC2A1 | 1200.57 | 1211.32 | 1281.16 | 1.07 | 1.06 | 1.04 |
| hypoxia-inducible factor 1, alpha | HIF1A | 3985.62 | 7783.65 | 2552.07 | -1.56 | -3.05 | -2.50 |
| vascular endothelial growth factor | VEGF | 1874.33 | 5661.88 | 2233.09 | 1.19 | -2.54 | -1.86 |
| CD24 molecule | CD24 | 521.84 | 44.59 | 86.75 | -6.02 | 1.95 | -3.42 |
| keratin 19 | KRT19 | 0.91 | 0.65 | 32.59 | 35.81 | 50.47 | 19.88 |
| glypican 3 | GPC3 | 4.24 | 37.63 | 13.28 | 3.13 | -2.83 | -1.78 |
| annexin A3 | ANXA3 | 7.64 | 63.66 | 8.26 | 1.08 | -7.71 | -7.44 |
| pleiotrophin | PTN | 208.08 | 54.11 | 1.10 | -189.18 | -49.19 | -152.58 |
| vimentin | VIM | 4625.18 | 4749.33 | 3508.86 | -1.32 | -1.35 | -1.35 |
| cartilage oligomeric matrix protein | COMP | 6053.50 | 2986.89 | 2786.96 | -2.17 | -1.07 | -1.78 |
| matrix Gla protein | MGP | 8480.52 | 7742.10 | 2865.30 | -2.96 | -2.70 | -3.21 |
| alpha-2-macroglobulin | A2M | 9.49 | 26.62 | 11.37 | 1.20 | -2.34 | -1.77 |
| annexin A4 | ANXA4 | 1223.21 | 2318.40 | 1273.29 | 1.04 | -1.82 | -1.55 |
| desmocollin 2 | DSC2 | 1.88 | 140.72 | 68.18 | 36.30 | -2.06 | -1.22 |
| keratin 18 | KRT18 | 0.01 | 0.04 | 94.10 | 15990.45 | 2647.60 | 1860.77 |
| neural cell adhesion molecule 1 | NCAM1 | 0.76 | 0.94 | 12.64 | 16.55 | 13.43 | 10.06 |
