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Table 4 Previously identified marker

From: Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes

Gene description Gene symbol AC mean AF mean NP mean Fold change (NP/AC) Fold change (NP/AF) Fold change (NP/AC&AF)
matrix metallopeptidase 2 MMP2 200.20 155.41 121.53 -1.65 -1.28 -1.56
solute carrier family 2, member 1 SLC2A1 1200.57 1211.32 1281.16 1.07 1.06 1.04
hypoxia-inducible factor 1, alpha HIF1A 3985.62 7783.65 2552.07 -1.56 -3.05 -2.50
vascular endothelial growth factor VEGF 1874.33 5661.88 2233.09 1.19 -2.54 -1.86
CD24 molecule CD24 521.84 44.59 86.75 -6.02 1.95 -3.42
keratin 19 KRT19 0.91 0.65 32.59 35.81 50.47 19.88
glypican 3 GPC3 4.24 37.63 13.28 3.13 -2.83 -1.78
annexin A3 ANXA3 7.64 63.66 8.26 1.08 -7.71 -7.44
pleiotrophin PTN 208.08 54.11 1.10 -189.18 -49.19 -152.58
vimentin VIM 4625.18 4749.33 3508.86 -1.32 -1.35 -1.35
cartilage oligomeric matrix protein COMP 6053.50 2986.89 2786.96 -2.17 -1.07 -1.78
matrix Gla protein MGP 8480.52 7742.10 2865.30 -2.96 -2.70 -3.21
alpha-2-macroglobulin A2M 9.49 26.62 11.37 1.20 -2.34 -1.77
annexin A4 ANXA4 1223.21 2318.40 1273.29 1.04 -1.82 -1.55
desmocollin 2 DSC2 1.88 140.72 68.18 36.30 -2.06 -1.22
keratin 18 KRT18 0.01 0.04 94.10 15990.45 2647.60 1860.77
neural cell adhesion molecule 1 NCAM1 0.76 0.94 12.64 16.55 13.43 10.06
  1. Bovine microarray data for previously identified markers. Mean fluorescence intensity expression is shown for each cell type (AC, AF and NP) along with the calculated fold change values. AC, articular cartilage; AF, annulus fibrosus; NP, nucleus pulposus.
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Arthritis Research & Therapy

ISSN: 1478-6362

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