Table 2 Joint inflammation and bone destruction
From: Functional consequences of DECTIN-1early stop codon polymorphism Y238X in rheumatoid arthritis
Variable | n | Homozygous wild-type for DECTIN-1 | n | Heterozygous for DECTIN-1Y238X | Pvalue |
|---|---|---|---|---|---|
Age (years) | 221 | 53 (14) | 41 | 53 (13) | 0.87 |
Female | 221 | 147 (66%) | 41 | 25 (61%) | 0.49 |
Rheumatoid factor + | 220 | 163 (74%) | 41 | 34 (83%) | 0.23 |
DAS28 baseline | 212 | 5.2 (1.5) | 40 | 5.3 (1.4) | 0.55 |
Average DAS28 year 0-3 | 214 | 3.9 (1.1) | 41 | 4.1 (1.2) | 0.37 |
Average DAS28 year 4-6 | 203 | 3.5 (1.1) | 35 | 3.9 (1.3) | 0.05 |
Average DAS28 year 7-9 | 166 | 3.5 (1.2) | 28 | 4.0 (1.3) | 0.07 |
Joint-damage score baseline | 221 | 0 (0-2) | 41 | 0 (0-3) | 0.87 |
Joint-damage score year 3 | 221 | 6 (1-15) | 41 | 5 (0-18) | 0.70 |
Joint-damage score year 6 | 154 | 13 (2-26) | 29 | 14 (3-26) | 0.98 |
Joint-damage score year 9 | 109 | 20 (8-35) | 24 | 20 (3-37) | 0.98 |