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Table 2 Absolute number of stem cells and circulating endothelial progenitor cells in peripheral blood (cells per 106 lineage-negative mononuclear cells)

From: Enhanced late-outgrowth circulating endothelial progenitor cell levels in rheumatoid arthritis and correlation with disease activity

Cells per 106 Lin- mononuclear cells RA patients (n = 59) Controls (n = 36) Pvalue
Lin-/7AAD-/CD34+/CD133+    0.0002
   Median (range) 2,484 (213-26,613) 1,068 (123-2,270)  
   25%-75% percentile 1,141-5,943 610.5-1,575  
Lin-/7AAD-/CD34+/VEGFR-2+    0.0026
   Median (range) 259 (27-588) 103 (11-1,105)  
   25%-75% percentile 124-493 49.75-193.8  
Lin-/7AAD-/CD133+/VEGFR-2+    0.0276
   Median (range) 151 (45-964) 125 (25-555)  
   25%-75% percentile 93-387 99.25-192.8  
Lin-/7AAD-/CD34+/CD133+/VEGFR-2+ (EPCs)    0.0007
   Median (range) 112 (27-588) 60 (5-275)  
   25%-75% percentile 53-227 26-109.8  
Lin-/7AAD-/CD105+/CD133-/VEGFR-2+(CECs)    0.1727
   Median (range) 173 (12-989) 139 (30-426)a  
   25%-75% percentile 57-341 73-189  
Ratio EPCs/CECs, median (range) 1 (0.07-4.28) 1 (0.2-2.02)a 0.3946
  1. aCirculating endothelial cell (CEC) number has been evaluated in 15 healthy controls. 7AAD, 7-aminoactinomycin D; DAS-28, 28-joint disease activity score; EPC, endothelial progenitor cell; Lin-, lineage-negative; RA, rheumatoid arthritis; VEGFR-2, vascular endothelial growth factor receptor-2.