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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells

Figure 2

Effects of pentosan polysulfate on proteoglycan synthesis in mesenchymal precursor stem cell micromass cultures. Bar graphs showing the temporal and concentration effects of pentosan polysulfate (PPS) on the biosynthesis of proteoglycans (determined as sulfated glycosaminoglycans (35S-GAGs)) by mesenchymal precursor stem cells (MPCs) in micromass cultures for 5, 7 and 10 days. Data (mean ± standard deviation) presented as percentage of control calculated from the 35S-GAG DPM/μg DNA values at each PPS concentration (n = 6). ‡P < 0.05, *P < 0.01; **P < 0.001; ***P < 0.0001 relative to control cultures.

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