Figure 7From: Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cellsEffects of pentosan polysulfate on gene expression by mesenchymal precursor stem cells in micromass cultures. Bar graphs showing the concentration effects of pentosan polysulfate (PPS) on (a) SOX-9, (b) Aggrecan, (c) collagen type II, (d) collagen type I, (e) collagen type X, (f) RUNX2 (Cbfa1) and (g) Noggin gene expression by mesenchymal precursor stem cells (MPCs) in micromass cultures for 7 and 10 days as determined by real-time quantitative PCR. n = 3 for each PPS concentration. Data expressed as mean ± standard deviation for each PPS concentration after normalising for the expression of the housekeeping gene, β-actin. #P < 0.05, *P < 0.01, **P < 0.001, ***P < 0.0001 gene expression relative to control.Back to article page