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Table 1 Biochemical parameters in 35 patients with verified systemic sclerosis, grouped according to pulmonary involvement and duration of disease

From: Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma)

Biochemical

Group Aa

Group Ba

 

parameter

n = 12

n = 23

 

Propeptide (%NPP)

150

120

P < 0.02

 

(87–360)

(72–167)

 

vWf (%NPP)

210

146

ns

 

(66–670)

(58–459)

(P = 0.32)

CRP (mg/l)

11

5

ns

 

(5–88)

(5–32)

(P = 0.052)

Orosomucoid (g/l)

1.07

0.87

P < 0.05

 

(0.81–1.89)

(0.42–1.15)

 

ESR (mm/h)

21

14

ns

 

(2–70)

(4–70)

(P = 0.12)

PIIINP (μg/l)

5.8

4.0

ns

 

(3.0–17.0)

(1.5–10.5)

(P = 0.07)

  1. Values are shown as median (range). P values indicate the difference between group A and group B; ns = not significant. aGroup A consisted of patients with short disease duration (≤ 1 year) and pulmonary involvement. Group B consisted of the remaining patients.
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Arthritis Research & Therapy

ISSN: 1478-6362

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