Skip to main content
Figure 1 | Arthritis Research & Therapy

Figure 1

From: Gait changes precede overt arthritis and strongly correlate with symptoms and histopathological events in pristane-induced arthritis

Figure 1

Gait analysis by CatWalk in a healthy rat. Time course of the print area (A) and the duration of stance phase measured as the fraction of total step duration (B) of all four paws in a 10-week-old female control rat walking across the CatWalk walkway. Front paws are shown with filled symbols, hind paws with open symbols. Extremities of the right side are indicated as squares, of the left side as circles. Gait variables are depicted in black, arthritis scores in red. (C) Picture of CatWalk footprints on Day 24 after injection of PBS. Prints of the left paws of the rat are shown in red, and prints of the right paws are shown in blue. Prints of front paws are depicted in lighter colour, whereas prints of the hind paws are darker. (D) Picture of the CatWalk gait diagram 24 days after PBS-injection. Indicated are the paw-floor contacts for each of the paws over time. The length of each bar represents the duration of the stance phase for that particular paw. The space between bars represents the duration of the swing phase. No conspicuous changes in gait variables were detected.

Back to article page