Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 3 Patient and disease characteristics in 5,493 individuals younger than 65 years who are working or not working in the QUEST-RA study in countries with a high (>24K USD) or low (<11K USD) GDP

From: Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA Study

  Individuals younger than 65 years old
  All countries High-GDP countries Low-GDP countries
  Working Not working P valuea Working Not working P valuea Working Not working P valuea
Number 2,590 2,903   1,436 1,347   1,154 1,556  
Patient characteristics          
   Females, percentage 76% 85% < 0.001 72% 81% < 0.001 82% 89% < 0.001
   Age in years, mean 46 52 < 0.001 47 54 < 0.001 45 50 < 0.001
   Disease duration in years, mean 8.3 11 < 0.001 8.7 12 < 0.001 7.8 11 < 0.001
   Rheumatoid factor-positive, percentage 72% 75% 0.004 70% 75% 0.001 75% 76% 0.64
   Erosive disease, percentage 53% 65% < 0.001 51% 62% < 0.001 56% 69% < 0.001
Disease activity measures          
   DAS28 (0 to 9.1), mean 4.0 4.6 < 0.001 3.3 3.9 < 0.001 4.8 5.2 < 0.001
   ESR, median 20 26 < 0.001 14 18 < 0.001 28 32 < 0.001
   SJC (0 to 28), median 2 3 < 0.001 1 2 < 0.001 3 4 0.002
   TJC (0 to 28), median 3 5 < 0.001 1 2 < 0.001 7 8 < 0.001
   Physician global (0 to 10), median 2.1 2.8 < 0.001 1.5 1.9 < 0.001 3.0 3.8 < 0.001
Patient self-report          
   HAQ physical function (0 to 3), median 0.63 1.1 < 0.001 0.50 0.88 < 0.001 0.88 1.3 < 0.001
   Pain VAS (0 to 10), median 3.2 4.5 < 0.001 2.3 3.8 < 0.001 4.2 4.9 < 0.001
   Patient global VAS (0 to 10), median 3.3 4.6 < 0.001 2.4 3.6 < 0.001 4.3 5.0 < 0.001
   Fatigue VAS (0 to 10), median 3.9 4.8 < 0.001 3.2 4.2 < 0.001 4.5 5.2 < 0.001
   Psychological HAQ (0 to 3), mean 0.79 0.94 < 0.001 0.60 0.82 < 0.001 0.87 1.1 < 0.001
Treatment-related variables          
   Number of DMARDs ever taken, mean 2.42 2.73 < 0.001 2.6 3.1 < 0.001 2.2 2.4 < 0.001
   Biologics ever, percentage of patients 22% 21% 0.60 32% 35% 0.12 8.5% 9.0% 0.65
  1. aUnadjusted P values are presented. DAS28, disease activity score using 28 joint counts; DMARD, disease-modifying antirheumatic drug; ESR, erythrocyte sedimentation rate; GDP, gross domestic product; HAQ, Health Assessment Questionnaire; QUEST-RA, Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis; SJC, swollen joint count; TJC, tender joint count; USD, US dollars; VAS, visual analog scale.