Effectiveness of adalimumab in treating patients with ankylosing spondylitis associated with enthesitis and peripheral arthritis

Table 1 Baseline characteristics in patients with ankylosing spondylitis by subgroup of enthesitis or peripheral arthritis or both

	Patient subgroups
Characteristic	No enthesitis + no arthritis (n = 457)	Enthesitis + no arthritis (n = 512)	Arthritis + no enthesitis (n = 107)	Enthesitis + arthritis (n = 174)
Age, years	43.1 ± 11.2	42.7 ± 11.1	46.0 ± 11.9	46.1 ± 12.3
Males, percentage	80.7	67.8	69.2	58.0
HLA-B27-positive, percentage	83.7	82.2	84.1	76.0
AS duration, years	10.9 ± 9.4	10.5 ± 9.7	12.3 ± 10.6	11.8 ± 10.5
Advanced AS, percentage	25.2	28.4	27.6	26.5
Concomitant NSAIDs, percentage	74.0	76.8	73.8	68.4
Concomitant DMARDs, percentage	21.7	22.1	45.8	35.6
Concomitant glucocorticoids^a, percentage	10.1	10.9	29.9	20.1
Prior TNF-antagonist therapy, percentage	25.8	25.0	27.1	29.3

Data are mean ± standard deviation unless otherwise noted. ^aSystemic treatment with not more than 10 mg of prednisone equivalent daily. AS, ankylosing spondylitis; DMARD, disease-modifying antirheumatic drug; NSAID, nonsteroidal anti-inflammatory drug; TNF, tumor necrosis factor.

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