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Table 3 MASES, tender joint count, and swollen joint count by sex, HLA-B27 positivity, and concomitant DMARD use

From: Effectiveness of adalimumab in treating patients with ankylosing spondylitis associated with enthesitis and peripheral arthritis

 

All

Male

Female

HLA-B27-negative

HLA-B27-positive

No concomitant DMARD at baseline

Concomitant DMARD at baseline

 

Median

First quartile, third quartile

[95% confidence interval]

Patients with enthesitis, MASES ≥ 1 at baseline

MASES: 0 to 13, number (percentage)

667

(100)

431

(64.6)

236

(35.4)

126

(18.9)a

523

(78.4)a

499

(74.8)

168

(25.2)

Baseline

5

2, 8

4

2, 7

7

4, 9

5

2, 9

5

2, 8

5

2, 8

4

2, 8

Week 12

1

0, 4

0

0, 2

1

0, 5

1

0, 5

0

0, 3

0

0, 3

1

0, 4

Change from baseline to week 12

-2

-5,-1

[-3 to -2]

-2

-5,-1

[-3 to -2]

-3

-6,-1

[-4 to -2]

-2

-5,-1

[-3 to -2]

-3

-6,-1

[-3 to -2]

-3

-5,-1

[-3 to -2]

-2

-5,-1

[-5 to -2]

Patients with peripheral arthritis, SJC ≥ 1 at baseline

TJC: 0 to 46, number (percentage)

281

(100)

175

(62.2)

106

(37.7)

57

(20.3)a

217

(77.2)a

170

(60.5)

111

(39.5)

Baseline

5

2, 12

4

2, 10

7

3, 14

6

3, 13

5

2, 12

4

2, 10

6

3, 13

Week 12

1

0, 3

1

0, 3

1

0, 4

1

0, 4

0

0, 3

0

0, 3

1

0, 4

Change from baseline to week 12

-3

-8,-1

[-4 to -2]

-2

-6,-1

[-3 to -2]

-4

-10,-2

[-6 to -3]

-3

-10,-1

[-6 to -2]

-3

-7,-1

[-4 to -2]

-2

-7,-1

[-3 to -2]

-3

-9,-2

[-4 to -2]

SJC: 0 to 44, number (percentage)

281

(100)

175

(62.2)

106

(37.7)

57

(20.3)a

217

(77.2)a

170

(60.5)

111

(39.5)

Baseline

2

1, 4

2

1, 3

2

1, 6

2

1, 6

2

1, 4

2

1, 3

2

1, 6

Week 12

0

0, 1

0

0, 1

0

0, 1

0

0, 1

0

0, 1

0

0, 1

0

0, 1

Change from baseline to week 12

-1

-3,-1

[-2 to -1]

-1

-3,-1

[-2 to -1]

-2

-4,-1

[-2 to -1]

-1

-4,-1

[-2 to -1]

-1

-3,-1

[-2 to -1]

-1

-2,-1

[-1 to -1]

-2

-4,-1

[-2 to -2]

  1. aBecause of missing data, the percentages of patients with HLA-B27 status do not sum to 100%. DMARD, disease-modifying antirheumatic drug; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score; SJC, swollen joint count; TJC, tender joint count.