Slit3 inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid arthritis

Table 1 Results from WTCCC RA GWAS in ROBO3 gene region

SNP	Position ^a	Pvalue ^b	Function
rs653403	124,201,501	0.329954	5' intergenic ROBO3
rs610104	124,213,908	0.217045	5' intergenic ROBO3
rs10790711	124,219,899	0.0341778	5' intergenic ROBO3
rs733601	124,220,090	0.762976	5' intergenic ROBO3
rs1940177	124,223,175	0.859324	5' intergenic ROBO3
rs11604758	124,226,213	0.00078241	5' intergenic ROBO3
rs11219814	124,233,333	0.184905	5' intergenic ROBO3
rs4936957	124,245,198	0.0184723	Intron 4ROBO3
rs3923890	124,245,620	0.00875808	Intron 5ROBO3
rs10790714	124,255,238	0.0629092	Intron 26 ROBO3
rs4326810	124,255,347	0.163546	Intron 26 ROBO3
rs12823	124,259,821	0.0722958	3' UTR ROBO4
rs11219831	124,267,979	0.421456	Intron 10 ROBO4
rs11219832	124,272,500	0.703442	Intron 1 ROBO4
rs4077566	124,276,481	0.0658315	5' intergenic ROBO4

^a on chromosome 11 (hg18).
^b additive model.
Nominal significant results are displayed in bold.
GWAS, genome-wide association study; RA, rheumatoid arthritis; SNP, single nucleotide protocol; WTCCC, Wellcome Trust Case Control Consortium.

ISSN: 1478-6362