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Table 3 Patients' demographics, autoimmune profile and co-morbidities by disease category

From: Anticentromere antibody positive Sjögren's Syndrome: a retrospective descriptive analysis

Characteristics of patients (P-value1) ACA+/SS
(n = 20) [%]
SSc/(+) sicca
(n = 31) [%]
SSc/(-) sicca (n = 20) [%] ACA-/SS
(n = 61) [%]
Sex(0.558)     
female 20 [100.0] 28 [90.3] 19 [95.0] 57 [93.4]
male 0 [0.0] 3 [9.7] 1 [5.0] 4 [6.6]
P-values 2   0.271 1.000 0.567
Smoking (0.603) 4 [20.0] 5 [16.1] 2 [10.0] 14 [23.0]
P --values 2   0.703 0.661 1.000
Anti-Ro (<0.0001) 6 [30.0] 4 [12.9] 0 [0.0] 43 [70.5]
P-values 2   0.163 0.020 0.003
Anti-La (<0.0001) 3 [15.0] 2 [6.5] 0 [0.0] 25 [41.0]
P-values 2   0.369 0.231 0.056
ANA (0.006) 20 [100.0] 31 [100.0] 20 [100.0] 51 [83.6]
P-values 2   - - 0.060
Anti-U1RNP (0.558) 0 [0.0] 3 [9.7] 1 [5.0] 4 [6.6]
P-values 2   0.271 1.000 0. 567
Anti-Sm (0.721) 0 [0.0] 1 [3.2] 0 [0.0] 2 [3.3]
P-values 2   1.000 - 1.000
Anti-Scl70 (0.172) 0 [0.0] 2 [6.5] 1 [5.0] 0 [0.0]
P-values 2   0.514 1.000 -
Th. Hashimoto (0.023) 1 [5.0] 4 [12.9] 0 [0.0] 15 [24.6]
P-values 2   0.636 1.000 0.102
Autoim. Hepatitis (-) 0 [0.0] 0 [0.0] 0 [0.0] 0 [0.0]
P-values 2   - - -
Atr. gastritis (0.422) 2 [10.0] 2 [6.5] 0 [0.0] 2 [3.3]
P-values 2   0.640 0.487 0.254
PBC (0.209) 3 [15.0] 3 [9.7] 0 [0.0] 3 [4.9]
P-values 2   0.668 0.231 0.157
Celiac (0.209) 0 [0.0] 0 [0.0] 0 [0.0] 1 [1.6]
P-values 2   - - 1.000
Lymphoma (0.476) 0 [0.0] 2 [6.5] 0 [0.0] 2 [3.3]
P-values 2   0.514 - 1.000
Death (0.059) 0 [0.0] 3 [9.7] 1 [5.0] 0 [0.0]
P-values 2   0.271 1.000 -
  1. 1 Overall P-value from the Chi Square test of independence (significance < 0.05).
  2. 2 P-values from the Fisher's exact test comparing the first group with each of the other three groups
  3. PBC, primary biliary cirrhosis