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Table 3 Relation between increasing grade of severity of subchondral bone abnormality and tibial cartilage volume

From: The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study

 

No BML or cyst at baseline

Mean (95% CI)

With BML at baseline

Mean (95% CI)

With cyst at baseline

Mean (95% CI)

P for trend

Medial tibial cartilage volumea

1,923

(1,808, 2,038)

1,809

(1,640, 1,979)

1,589

(1,442, 1,735)

0.004

Lateral tibial cartilage volumeb

2,132

(2,028, 2,236)

1,962

(1,616, 2,309)

1,607

(1,399, 1,817)

<0.001

Medial tibial cartilage volume lossa

2.62

(0.82, 4.42)

6.30

(3.43, 9.17)

9.26

(6.78, 11.73)

<0.001

Lateral tibial cartilage volume lossb

5.88

(4.18, 7.59)

7.19

(1.46, 12.93)

2.42

(-1.00, 5.84)

0.17

  1. Volume expressed as cubic millimeters. Abnormality: 1, normal; 2, BML only; 3, both BML and cyst present. aAssociation with cysts and BMLs in the medial compartment. bAssociation with cysts and BMLs in the lateral compartment. Mean, 95% confidence interval, and P value were calculated by using Estimated Marginal Means. CI, confidence interval; BML, bone marrow lesion.