Skip to main content

Table 3 Relation between increasing grade of severity of subchondral bone abnormality and tibial cartilage volume

From: The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study

  No BML or cyst at baseline
Mean (95% CI)
With BML at baseline
Mean (95% CI)
With cyst at baseline
Mean (95% CI)
P for trend
Medial tibial cartilage volumea 1,923
(1,808, 2,038)
1,809
(1,640, 1,979)
1,589
(1,442, 1,735)
0.004
Lateral tibial cartilage volumeb 2,132
(2,028, 2,236)
1,962
(1,616, 2,309)
1,607
(1,399, 1,817)
<0.001
Medial tibial cartilage volume lossa 2.62
(0.82, 4.42)
6.30
(3.43, 9.17)
9.26
(6.78, 11.73)
<0.001
Lateral tibial cartilage volume lossb 5.88
(4.18, 7.59)
7.19
(1.46, 12.93)
2.42
(-1.00, 5.84)
0.17
  1. Volume expressed as cubic millimeters. Abnormality: 1, normal; 2, BML only; 3, both BML and cyst present. aAssociation with cysts and BMLs in the medial compartment. bAssociation with cysts and BMLs in the lateral compartment. Mean, 95% confidence interval, and P value were calculated by using Estimated Marginal Means. CI, confidence interval; BML, bone marrow lesion.