The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study

Table 4 Effect of increasing grade of severity of subchondral bone abnormality on joint replacement

	Univariate analysis OR (95% CI)	Pvalue	Multivariate analysis^a OR (95% CI)	P value
Medial TF compartment	1.72 (0.93 to 3.18)	0.08	1.99 (1.01 to 3.90)	0.05
Lateral TF compartment	0.95 (0.48 to 1.88)	0.89	0.96 (0.48 to 1.94)	0.91

Abnormality: 1, normal; 2, BML only; 3, both BML and cyst present. ^aAdjusted for age, gender, and Kellgren-Lawrence grade. OR, odds ratio; CI, confidence interval; TF, tibiofemoral.

ISSN: 1478-6362