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Figure 6 | Arthritis Research & Therapy

Figure 6

From: FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development

Figure 6

Adoptive cell transfer of FoxP3- and Bcl-xL-transduced regulatory T cells decreases arthritis-specific antibody production. The treatment of adoptive cell transfer for collagen-induced arthritis is described in the legend of Figure 5. On day 60 of immunization, sera were separated from all samples and the levels of serum total IgG and anti-bovine type II collagen antibodies were determined by enzyme-linked immunosorbent assay. (a) Total IgG. (b) IgG1. (c) IgG2a. Values are the mean ± standard error of the mean (n = 6). Data are representative of two similar experiments (*P <0.05, Student unpaired t test). OD, optical density.

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