Table 3 Association of rs1805010 and rs1801275 with radiographic erosions after stratification by the presence of HLA-DRB1 SE and autoantibodies in African Americans with RA
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
Erosiona n(%) | No erosion n(%) | Crude OR (95% CI) | P | Adjustedc OR (95% CI) | P | |
rs1805010, n (%) | n = 65b† | n = 74b | ||||
AA | 15 (23.1) | 15 (20.3) | 0.89 (0.34 to 2.36) | 0.82 | 0.95 (0.32 to 2.86) | 0.93 |
AG | 31 (47.7) | 42 (56.8) | 0.66 (0.30 to 1.47) | 0.31 | 0.81 (0.33 to 1.99) | 0.65 |
GG | 19 (29.2) | 17 (22.9) | 1.00 | -- | 1.00 | -- |
rs1801275, n (%) | n = 65b | n = 75b | ||||
AA | 3 (4.6) | 9 (12.0) | 0.31 (0.08 to 1.26) | 0.10 | 0.30 (0.06 to 1.47) | 0.14 |
AG | 28 (43.1) | 34 (45.3) | 0.78 (0.39 to 1.55) | 0.47 | 0.64 (0.30 to 1.40) | 0.27 |
GG | 34 (52.3) | 32 (42.7) | 1.00 | -- | 1.00 | -- |