Skip to main content

Table 2 Logistic regression analysis exploring the relationship between anti-CCP/IgM RF and persistent arthritic disease

From: The likelihood of persistent arthritis increases with the level of anti-citrullinated peptide antibody and immunoglobulin M rheumatoid factor: a longitudinal study of 376 patients with very early undifferentiated arthritis

 

Univariate

Multivariate*

 

estimate

OR

(95% CI)

P

estimate

OR

(95% CI)

P

Anti-CCP2

(units/ml)

0.013

1.013

(1.008 to 1.018)

<0.001

0.008

1.008

(1.003 to 1.013)

0.002

Anti-CCP2+

(>25 units/ml)

2.102

8.184

(4.008 to 16.709)

<0.001

1.272

3.567

(1.572 to 8.094)

0.002

IgM RF (units/ml)

0.022

1.022

(1.012 to 1.033)

<0.001

0.009

1.009

(1.001 to 1.017)

0.026

IgM RF+ (>25 units/ml)

2.018

7.526

(3.677 to 15.407)

<0.001

0.999

2.716

(1.189 to 6.202)

0.018

IgM RF+ and anti-CCP+

2.593

13.369

(4.658 to 38.369)

<0.001

2.073

7.948

(2.659 to 23.752)

<0.001

  1. *Adjusted for age, sex, small joint arthritis (swelling of MTP-, PIP- and/or MCP joints), Health Assessment Questionnaire, 28-tender joint count, C-reactive protein (mg/l), morning stiffness >1 hour, as well as IgM rheumatoid factor (for the analysis with anti-CCP) or anti-CCP (for the analysis with IgM RF), respectively.