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Table 5 Univariate logistic regression for persistent arthritis with anti-CCP/IgM RF as categorical (grouped) variables according to level

From: The likelihood of persistent arthritis increases with the level of anti-citrullinated peptide antibody and immunoglobulin M rheumatoid factor: a longitudinal study of 376 patients with very early undifferentiated arthritis

Anti-CCP (units/ml)

OR (95% C.I.)

P

LR+

LR-

Persistent arthritis patients/patients in category

n/N

≤ 25

1.0

 

ref

ref

122/314 (38.9%)

>25 to 100

4.4 (1.6 to 12.5)

0.005

4.1 (1.5 to 11.0)

0.9 (0.9 to 1.0)

14/19 (73.7%)

>100 to 250

9.4 (2.1 to 42.9)

0.004

8.7 (2.0 to 38.2)

0.9 (0.8 to 1.0)

12/14 (85.7%)

>250

13.6 (4.0 to 46.0)

<0.001

11.4 (3.5 to 37.0)

0.8 (0.8 to 0.9)

26/29 (89.7%)

IgM RF (units/ml)

OR (95% C.I.)

P

LR+

LR-

 

≤ 25

1.0

 

ref

ref

125/317 (39.4%)

>25 to 75

4.6 (2.0 to 10.6)

<0.001

4.0 (1.9 to 8.7)

0.9 (0.8 to 0.9)

24/32 (75.0%)

>75

19.2 (4.5 to 82.5)

<0.001

16.2 (3.9 to 67.2)

0.8 (0.8 to 0.9)

25/27 (92.6%)

  1. CI: confidence interval; LR+: positive likelihood ratio; LR-: negative likelihood ratio; OR, odds ratio