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Table 5 Univariate logistic regression for persistent arthritis with anti-CCP/IgM RF as categorical (grouped) variables according to level

From: The likelihood of persistent arthritis increases with the level of anti-citrullinated peptide antibody and immunoglobulin M rheumatoid factor: a longitudinal study of 376 patients with very early undifferentiated arthritis

Anti-CCP (units/ml) OR (95% C.I.) P LR+ LR- Persistent arthritis patients/patients in category
n/N
≤ 25 1.0   ref ref 122/314 (38.9%)
>25 to 100 4.4 (1.6 to 12.5) 0.005 4.1 (1.5 to 11.0) 0.9 (0.9 to 1.0) 14/19 (73.7%)
>100 to 250 9.4 (2.1 to 42.9) 0.004 8.7 (2.0 to 38.2) 0.9 (0.8 to 1.0) 12/14 (85.7%)
>250 13.6 (4.0 to 46.0) <0.001 11.4 (3.5 to 37.0) 0.8 (0.8 to 0.9) 26/29 (89.7%)
IgM RF (units/ml) OR (95% C.I.) P LR+ LR-  
≤ 25 1.0   ref ref 125/317 (39.4%)
>25 to 75 4.6 (2.0 to 10.6) <0.001 4.0 (1.9 to 8.7) 0.9 (0.8 to 0.9) 24/32 (75.0%)
>75 19.2 (4.5 to 82.5) <0.001 16.2 (3.9 to 67.2) 0.8 (0.8 to 0.9) 25/27 (92.6%)
  1. CI: confidence interval; LR+: positive likelihood ratio; LR-: negative likelihood ratio; OR, odds ratio