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Table 4 FMD, NMD and IMT in MCTD patients with/without cardiovascular disease and controls

From: Endothelial cell markers reflecting endothelial cell dysfunction in patients with mixed connective tissue disease

  %FMDa Pvalue %NMDa Pvalue IMTa Pvalue
Age at investigation (years) -0.0221 0.878 -0.6700 0.001 0.5468 0.001
Disease duration (years) -0.6468 0.001 -0.1314 0.3628 0.1968 0.1706
Systolic blood pressure (mmHg) -0.5423 0.001 -0.1094 0.4492 0.2220 0.1211
Diastolic blood pressure (mmHg) 0.0946 0.5133 0.1005 0.4872 -0.1597 0.2676
Serum triglycerides (mmol/l) -0.3396 0.0158 0.2165 0.1309 -0.0411 0.7765
Serum cholesterol -0.0459 0.7514 0.0508 0.7255 -0.0209 0.8851
Apolipoprotein A1 (g/l) 0.6203 0.001 -0.0805 0.5782 -0.0248 0.8640
Apolipoprotein B (g/l) -0.3102 0.061 -0.0891 0.5997 0.0767 0.6517
Paraoxonase-1 activity 0.5957 0.001 0.1317 0.3619 -0.2789 0.0497
hs-CRP -0.4057 0.003 -0.3207 0.023 0.7164 0.001
ESR -0.4283 0.001 -0.3981 0.001 0.5467 0.001
Anti-U1RNP (U/ml) -0.0486 0.7371 -0.0694 0.6316 0.4182 0.0025
Anti-CL IgG (U/ml) -0.0717 0.6206 -0.0411 0.776 0.2236 0.1184
AECA (IU/ml) -0.3075 0.029 -0.2686 0.0592 0.2890 0.0417
Thrombomodulin (ng/ml) -0.0642 0.6577 -0.0165 0.9089 0.4823 0.00038
vWFAg (%) -0.0122 0.9329 -0.2692 0.058 0.5443 0.001
  1. AECA, anti-endothelial cell antibody; anti-CL, anti-cardiolipin; anti-U1RNP, anti-U1 ribonucleoprotein; ESR, erythrocyte sedimentation rate; FMD, flow-mediated dilation; hs-CRP, high-sensitivity C-reactive protein; IMT, intima-media thickness; MCTD, mixed connective tissue disease; NMD, nitrate-mediated dilation; vWFAg, von Willebrand factor antigen. aSpearman rank correlation.
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