Table 5 Sensitivity analysis for the effect size on pain at post treatment
Outcome title | Number of study arms | Number of patients on aerobic exercise | Effect sizea | Test for overall effect, Pvalue | Heterogeneity, I2; Ï„2 (%) |
|---|---|---|---|---|---|
Adequate sequence generation | Â | Â | Â | Â | Â |
   Adequate | 11 | 251 | -0.20 (-0.38, -0.01) | 0.04 | 0; 0 |
   Unclear or nonadequate | 18 | 348 | -0.39 (-0.61, -0.18) | 0.0004 | 39; 0.07 |
Allocation concealment | Â | Â | Â | Â | Â |
   Adequate | 8 | 223 | -0.24 (-0.47, -0.01) | 0.04 | 24; 0.02 |
   Unclear or nonadequate | 19 | 344 | -0.35 (-0.54, -0.16) | 0.0002 | 28; 0.04 |
Blinding of assessor | Â | Â | Â | Â | Â |
   Yes | 12 | 306 | -0.20 (-0.36,-0.03) | 0.02 | 0; 0 |
   No or unclear | 15 | 261 | -0.41 (-0.66,-0.16) | 0.001 | 38;0.08 |
ITT analysis | Â | Â | Â | Â | Â |
   Yes | 13 | 315 | -0.22 (-0.39, -0.06) | 0.009 | 0; 0 |
   No | 14 | 252 | -0.39 (-0.62, -0.16) | 0.001 | 36; 0 |
Adequacy of outcomes for meta-analysis | Â | Â | Â | Â | Â |
   Yes (means) | 24 | 517 | -0.35 (-0.51,-0.19) | <0.0001 | 28;0.04 |
   No (medians) | 3 | 43 | -0.05 {-0.43,-0.32) | 0.78 | 0; 0 |
Sample size | Â | Â | Â | Â | Â |
   <25 | 3 | 30 | -0.33 (-1.00,0.33) | 0.33 | 34; 0.12 |
   25 to 50 | 15 | 188 | -0.41 (-0.70,-0.13) | 0.005 | 46;0.11 |
   >50 | 9 | 349 | -0.23 (-0.39,-0.08) | 0.004 | 0; 0 |
Patients with mental disorders included | Â | Â | Â | Â | Â |
   Yes | 16 | 312 | -0.43 (-0.78, -0.08) | 0.02 | 73; 0.28 |
   No or unclear | 14 | 315 | -0.40 (-0.61, -0.19) | 0.0002 | 38; 0.05 |